Despite its aspirational title, the Toxic Substances Control Act (TSCA) has failed to assess, let alone guarantee, the safety of the great majority of chemicals in use today. TSCA stymies action by EPA and other agencies, perpetuates a reliance on dangerous substances, leaves businesses in the dark, and undermines U.S. competitiveness. Adopted by Congress over 30 years ago, TSCA today is failing to protect the health of Americans, our children, and their children. So I am especially grateful for this opportunity to discuss with you today practical improvements that can bring TSCA into the 21st Century. In the current debate over TSCA reform, there is broad agreement that the United States must set priorities if we are to succeed in safely managing chemicals. I would like to offer three recommendations.